[-BoreSight-]

I use something a little more unconventional for FPS. It allows for maximum relaxation of the left hand. I just set my hand on the keyboard; naturally, my ring-finger rests on "A" and my index-finger on "C".
SHIFT - forward
A - Strafe left
S - Strafe right
C - Jump
SPACE - Crouch
Q - lean left
W - lean right
D - move back
R - reload
V - use

To each his own I guess. My advice is to make sure your most commonly used keys are "short throughs", this will reduce fatigue.

I really need to go outside once in a while